Product ID:TORADOL IM INJECTABLE
MSDS Date:10/09/1992
FSC:6505
NIIN:01-357-5375
MSDS Number: BWMLG

SYNTEX LABORATORIES INC

3401 HILLVIEW AVE
PALO ALTO, CA 94304-1320
US

Emergency Phone: 415-796-5050

Info Phone: 415-796-5050

Cage: NO495

SYNTEX LABORATORIES INC

PALO ALTO, CA 94304-1320 US

Telephone: 415-796-5050

Cage: NO495

KETOROLAC TROMETHAMINE

CAS: 74103-07-4

Fraction By Weight: 1.5-3%

ETHYL ALCOHOL (ETHANOL)

CAS: 64-17-5

RTECS: KQ6300000

OSHA PEL 1000 PPM

ACGIH TLV: 1000 PPM; 9394

SODIUM CHLORIDE

CAS: 7647-14-5

RTECS: VZ4725000

WATER

CAS: 7732-18-5

RTECS: ZC0110000

SODIUM HYDROXIDE (SARA III); AS NEEDED TO ADJUST PH.

CAS: 1310-73-2

RTECS: WB4900000

OSHA PEL 2 MG/M3

ACGIH TLV: C 2 MG/M3; 9394

EPA Report Quantity: 1000 LBS

DOT Report Quantity: 1000 LBS

HYDROCHLORIC ACID; AS NEEDED TO ADJUST PH.

CAS: 7647-01-0

RTECS: MW4025000

EPA Report Quantity: 5000 LBS

DOT Report Quantity: 5000 LBS

Routes of Entry: Inhalation:YES Skin:YES Ingestion:YES
Reports of Carcinogenicity:NTP:NO IARC:YES OSHA:NO
Health Hazards Acute and Chronic:ACUTE: TORADOL IM INJECTABLE IS
EXPECTED TO HAVE LOW ORAL TOXICITY. CHRONIC: REPEATED DOSE STUDIES
OF KETOROLAC TROMETHAMINE HAS CAUSED GASROINTESTINAL IRRITATION
AND/OR ULCERATION WHICH, AT HIGH DOS ES, SOMETIMES LED TO
PERITONITIS, ANEMIA, AND DEATH. HIGH LEVELS OF ETHANOL HAS
RESULTED IN NERVOUS SYSTEM EFFECTS.
Explanation of Carcinogenicity:ETHANOL IS LISTED BY IARC AS A
CARCINOGEN. NO OTHER COMPONENTS ARE LISTED. NO EVIDENCE OF
CARCINOGENICITY OBSERVED.
Effects of Overexposure:PRINCIPAL EFFECTS WERE GASTROINTESTINAL
COMPLAINTS (NAUSEA, VOMITING, AND DIARRHEA) AND CENTRAL NERVOUS
SYSTEM EFFECTS (DROWSINESS, INSOMNIA, HEADACHE, AND DIZZINESS).
Medical Cond Aggravated by Exposure:ALLERGY TO NON-STEROIDAL
ANTI-INFLAMMATORY DRUGS (E.G., ASPIRIN).

First Aid:EYES: IMMEDIATELY FLUSH WITH RUNNING WATER FOR AT LEAST 15
MINUTES WHILE LIFTING EYELIDS OPEN. SKIN: WASH WITH SOAP AND
PLENTY OF WATER. INHALATION: REMOVE TO FRESH AIR. INGESTION:
CONTACT A PHYSIC IAN OR POISON CONTROL CENTER. DRINK A MODERATE
AMOUNTS OF WATER.

Flash Point:120F,49C
Lower Limits:3.3
Upper Limits:19 (ETHANOL)
Extinguishing Media:WATER, MULTIPURPOSE DRY CHEMCIAL OR HALON FIRE
EXTINGUISHER.
Fire Fighting Procedures:WEAR A NIOSH APPROVED SELF-CONTAINED BREATHING
APPARATUS AND FULL PROTECTIVE EQUIPMENT WHEN FIGHTING FIRES. USE
WATER SPRAY TO COOL FIRE EXPOSED CONTAINERS.
Unusual Fire/Explosion Hazard:WASH ALL EQUIPMENT THOROUGHLY AFTER USE.

Spill Release Procedures:PROVIDE VENTILATION & CONFINE SPILL. DO NOT
ALLOW RUNOFF TO SEWER. CLEAN-UP PERSONNEL SHOULD USE RESPIRATORY
AND LIQUID CONTACT PROTECTION. KEEP COMBUSTIBLES AWAY FROM SPILLED
MATERIAL. ABSORB IN VERM ICULITE, DRY SAND OR EARTH & PLACE
INTOCONTAINER.

Handling and Storage Precautions:AVOID EXCESSIVE CONTACT WITH SKIN,
EYES OR CLOTHING. USE ADEQUATED VENTILATION TO MINIMIZE EXPOSURE.
WASH THOROUGHLY AFTER HANDLING.
Other Precautions:STORE IN A COOL, DRY AREA.

Respiratory Protection:NONE NORMALLY REQUIRED. WEAR A
NIOSH/MSHA-APPROVED HALF-FACE AIR PURIFYING RESPIRATOR FOR DUSTS,
MISTS AND ORGANIC VAPORS IF INHALATION EXPOSURE IS LIKELY.
Ventilation:NORMAL ROOM VENTILATION SHOULD BE ADEQUATE.
Protective Gloves:NONE NORMALLY REQUIRED.
Eye Protection:NONE NORMALLY REQUIRED.
Other Protective Equipment:DURING CLEANUP OF SPILLS, USE GLOVES, SAFETY
GLASSES WITH SIDE SHIELDS OR OTHER PROTECTIVE GARMENT.
Work Hygienic Practices:WASH HANDS THOROUGHLY AFTER HANDLING THIS
MATERIAL.
Supplemental Safety and Health

HCC:F4
pH:7.4
Appearance and Odor:CLEAR TO SLIGHTLY YELLOW LIQUID.

Stability Indicator/Materials to Avoid:YES
STRONG OXIDIZING AGENTS.
Stability Condition to Avoid:NOT GUARANTEED BEYOND EXPIRATION DATE
IMPRINTED ON PACKAGE. AVOID SPARKS AND OTHER SOURCES OF IGNITION.
Hazardous Decomposition Products:CARBON MONOXIDE, CARBON DIOXIDE.

Waste Disposal Methods:DISPOSE IN ACCORDANCE WITH FEDERAL, STATE AND
LOCAL REGULATIONS. ALL WASTES CONTAINING THE MATERIAL SHOULD BE
PROPERLY LABELED AND STORED SEPARATELY FROM OTHER WASTES.
RINSEWATER RESULTING FROM SPIL L CLEANUPS SHOULD BE DISCHARGED IN A
SAFE MANNER.

Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.